Abdelhalim Larhlimi

Maître de Conférences (Ass. Professor)
Computer Science Department
The University of Nantes
Member of the COMBI team in the research lab LINA

Selected publications

Basler G, Nikoloski Z, Larhlimi A, Barabási AL, Liu YY: Control principles of metabolic networks. Genome Research, accepted, 2016
Guidi L, Chaffron S, Bittner L, Eveillard D, Larhlimi A, Roux S et al., Plankton network driving carbon export in the oligotrophic ocean. Nature. doi: 10.1038/nature16942, 2016
Budinich M, Bourdon J, Larhlimi A, Eveillard E: Evolutionary Constraint-Based Formulation Requires New Bi-Level Solving Techniques. Computational Methods in Systems Biology, CMSB’15, Nantes, Springer LNBI 9308:279-281, 2015
Basler G, Larhlimi A, Grimbs S , Nikoloski Z: Computational metabolic engineering of Arabidopsis thaliana for increased biomass production. IWBBIO, 2013
Sulpice R, Nikoloski Z, Tschoep H, Antonio C, Kleessen S, Larhlimi A, Selbig J, Ishihara H, Gibon Y, Fernie AR and Stitt M: Impact of the Carbon and Nitrogen Supply on Relationships and Connectivity between Metabolism and Biomass in a Broad Panel of Arabidopsis Accessions. Plant Physiology, 162(1):347-363, 2013
Larhlimi A, Basler G, Grimbs S, Selbig J, and Nikoloski Z: Stoichiometric capacitance reveals the theoretical capabilities of metabolic networks. Bioinformatics, 28(18): I502-I508. 11th European Conference on Computational Biology (ECCB), Basel, Switzerland, 2012
Hische M, Larhlimi A, Schwarz F, Fischer-Rosinsky A, Bobbert T, Assmann A, Catchpole GS, Pfeiffer AFH, Willmitzer L, Selbig J and Spranger J: A distinct metabolic signature predicts development of fasting plasma glucose. J Clin Bioinforma ; 2(1) :3, 2012
Larhlimi A, David L, Selbig J, Bockmayr A: F2C2: a fast tool for the computation of flux coupling in genome-scale metabolic networks. BMC Bioinformatics 13:57, 2012
Schudoma C, Larhlimi A and Walther D: The influence of the local sequence environment on RNA loop structures. RNA ;17(7) :1247-57, 2011
Hoehenwarter W, Larhlimi A, Hummel J, Egelhofer V, Selbig J, van Dongen JT, Wienkoop S and Weckwerth WJ: MAPA distinguishes genotype-specific variability of highly similar regulatory protein isoforms in potato tuber. Proteome Res ;10(7) :2979-91, 2011.
David L, Marashi SA, Larhlimi A, Mieth B, Bockmayr A: FFCA: a feasibility-based method for flux coupling analysis of metabolic networks. BMC Bioinformatics 12:236, 2011
Larhlimi A, Blachon S, Selbig J and Nikoloski Z. Robustness of metabolic networks : a review of existing definitions. Biosystems ; 106(1) :1-8, 2011.
Larhlimi A and Bockmayr A: A new constraint-based description of the steady-state flux cone of metabolic networks. Discrete Applied Mathematics, 157, 2257-2266, 2009
Larhlimi A and Bockmayr A: On Inner and Outer Descriptions of the Steady-State Flux Cone of a Metabolic Network. Computational Methods in Systems Biology, CMSB 2008, Rostock. Springer, LNBI 5307, 308-327, 2008
Larhlimi A and Bockmayr A: Minimal Direction Cuts in Metabolic Networks, Computational Life Sciences III, CompLife'07, Utrecht, October 2007. AIP Conference Proceedings, Vol. 940, 73-86, 2007
Larhlimi A and Bockmayr A: Constraint-based Analysis of Gene Deletion in a Metabolic Network. Workshop on Constraint based Methods for Bioinformatics, WCB'07, Porto, 48-55, 2007
Larhlimi A and Bockmayr A: A New Approach to Flux Coupling Analysis of Metabolic Networks. Computational Life Sciences II, CompLife'06, Cambridge, UK. Springer LNBI 4216, 205-215, 2006

Last update May 18 2013